Background

The Challenge

  • Chronic lymphocytic leukemia (CLL) requires ongoing emotional and physical resilience, as patients often face uncertainty, fatigue, and the psychological burden of a long-term diagnosis.

  • The introduction of a new twice-daily oral treatment regimen added complexity to patients’ routines, requiring strict adherence on top of other self-management behaviors.

  • Patients need support not only to understand and accept their condition, but also to build confidence in managing symptoms, side effects, and lifestyle adjustments over time.

  • The MyCLL program was designed to improve the overall patient experience, helping individuals persist with their treatment plan while enhancing their ability to self-manage and maintain quality of life. 

Our Behavior Change Approach

  • Using the COM-B model we identified key behavioral drivers related to treatment adherence in CLL, and tailored the experience based on assessing each patient's drivers, needs and preferences.

  • We integrated the Brief Illness Perceptions Questionnaire (BIPQ) and a validated Quality of Life question to uncover patients’ beliefs, emotional responses, and perceived control over their condition.

  • The multichannel program provided digital self-management content addressing the needs and behavioral drivers, ensuring that each patient received relevant, meaningful support.

The Solution

The program experience over a 12 month journey included:

  • A personalized online portal providing a guided journey of emotional, behavioral and motivational support with a series of interactive e-Learning modules, articles, patient videos and stories as well as goal setting functionality​

  • Nurse videos providing expert advice throughout the patient journey

  • Treatment reminders and behavior change SMS messages helping patients to optimise treatment adherence​

  • An HCP feedback loop to ensure healthcare teams were informed of their patient’s progress

The Impact

Positive improvements were reported by participants:

  • 32% improvement in perceived emotional wellbeing of patients

  • Improved day-to-day self-management such as symptom control by 31%

  • Reduced overall illness concerns by 32%

  • Quality of life rating increased by 16% over baseline.

  • Program retention rate was 94.3%​.

  • Treatment persistence at 12 months was 94% ​for PSP patients compared to real-world data showing 81% with standard care.

Learn more about our personalized, multichannel behavior change solutions.