The challenge

To address the high level of non-persistence to oral anti-platelet (OAP) medication among people diagnosed with acute coronary syndrome (ACS), using a globally-designed personalized multichannel behavior change program.


A research and evidence-based approach identified unhelpful beliefs associated with OAP nonadherence. This included a literature review, plus multi-market qualitative and quantitative research with patients, physicians and cardiac nurses.

Proposed program materials were developed in collaboration with physicians and cardiac nurses from UK private and public hospitals.

Subsequent testing of the materials with ACS patients in other countries informed cultural adaptations.


Psychoeducational support, addressing individuals’ beliefs and challenges in living with ACS, was delivered via multiple channels over a six-month program journey. Behavior change techniques empowered adherence and adoption of practical skills and positive lifestyle behaviors including cardiac rehab attendance.

Each individual's profiling data was leveraged to personalize the  content and frequency of contact according to their specific needs.


The program positively impacted OAP persistence:

  • 99% at 3 months
  • 95% at 6 months
  • 83% at 12 months post-enrolment and treatment initiation.

This compares favourably with previous data reporting on OAP persistence of 34% at 12 months.

Program participants reported making positive lifestyle changes, with:

  • 68% increasing their level of physical activity;
  • 78% changing their diet; and
  • 100% had quit smoking.



The program was delivered to ACS patients across Australia, Germany, New Zealand, United Arab Emirates, and the United Kingdom.