Case study: Improving wellbeing and persistence through digital support for CLL patients
Background
The Challenge
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Chronic lymphocytic leukaemia (CLL) requires ongoing emotional and physical resilience, as patients often face uncertainty, fatigue, and the psychological burden of a long-term diagnosis.
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The introduction of a new twice-daily oral treatment regimen added complexity to patients’ routines, requiring strict adherence on top of other self-management behaviours.
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Patients need support not only to understand and accept their condition, but also to build confidence in managing symptoms, side effects, and lifestyle adjustments over time.
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The MyCLL programme was designed to improve the overall patient experience, helping individuals persist with their treatment plan while enhancing their ability to self-manage and maintain quality of life.
Our Behaviour Change Approach
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Using the COM-B model we identified key behavioural drivers related to treatment adherence in CLL, and tailored the experience based on assessing each patient's drivers, needs and preferences.
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We integrated the Brief Illness Perceptions Questionnaire (BIPQ) and a validated Quality of Life question to uncover patients’ beliefs, emotional responses, and perceived control over their condition.
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The multichannel programme provided digital self-management content addressing the needs and behavioural drivers, ensuring that each patient received relevant, meaningful support.
The Solution
The programme experience over a 12 month journey included:
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A personalised online portal providing a guided journey of emotional, behavioural and motivational support with a series of interactive e-Learning modules, articles, patient videos and stories as well as goal setting functionality
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Nurse videos providing expert advice throughout the patient journey
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Treatment reminders and behaviour change SMS messages helping patients to optimise treatment adherence
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An HCP feedback loop to ensure healthcare teams were informed of their patient’s progress
The Impact
Positive improvements were reported by participants:
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32% improvement in perceived emotional wellbeing
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Improved day-to-day self-management such as symptom control by 31%
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Reduced overall illness concerns by 32%
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Treatment persistence at 12 months was 94% for PSP patients compared to real-world data showing 81% with standard care.
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Quality of life rating increased by 16% over baseline.
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Program retention rate was 94.3%.
